He has collaborated as a musician and/or sound engineer with various artists like Federico Salvatore, Tiziano Ferro, Valeria Rossi, Nicola Piovani, Ennio Morricone, Antonio Pennacchi, Maurizio Battista, Daniele Vit, Andrea Febo, Gigi D’Alessio, Alyce, Elsa Lila, Lollipop, and Adriano De Pasquale. He has also collaborated with many labels like BMG Ariola, EMI Music, SONY Music, Orange Records, Azzurra Music, DFV, Medusa Film, and Kubla Khan.
Along with collaborations, he has also composed original soundtracks for The Shoes (Teatro Sistina, 1997), Rome, an infinite story with Carlo Verdone (1998), Without filter by and with Article 31 (2001), SuperStizion by Luciano Federico (2002), and Gradoli (2008).
Since 2002, he has been involved in the the music production and management for Federico Salvatore for whom he has produced three albums, a music DVD and the theater shows If I were San Gennaro (2012-2013) and And we shut up ( 2013-2015), on stage in Italy with more than 100 encores. Zaccheo has also been curating artistic productions of his own label called Orange Records.
He has been teaching music production and composition at the Saint Louis College of Music Sound Engineering department since 2002.